Genetics of Aging

Genetics of aging which deals with life extension and it is associated with genetic alterations which lead to changes in lifespan. There is an unparalleled rise in human life expectancy in the past two centuries. Sustaining longer survival will require an understanding of the topics like mechanisms of aging and genetics which is considered as a powerful tool for the identification of these mechanisms. The first mutation is found to increase longevity in an animal was the age-1 gene in Caenorhabditis elegans. Drosophila melanogaster lifespan has been doubled. Genetic mutations in mice may be increased to maximum lifespan of 1.5 times normal, and up to 1.7 times normal when it is combined with calorie restriction.

  • Genetic engineering
  • Genetic factors in aging
  • Life extension
  • Mutation

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